Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Syrup used to get relief from cold, allergies, and upper respiratory issues. The syrup combines two active ingredients: the Dextromethorphan Hydrobromide, which is a cough suppressant, and the Chlorpheniramine Maleate, which is an antihistamine. Both of them together in combination certainly create a potent cough syrup meant to target issues like dry cough, sneezing, runny nose, and throat irritation.
This article will give you a comprehensive guide on the Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Syrup Uses, benefits, dosage and side effects, and more
Dextromethorphan hydrobromide and chlorpheniramine Maleate: Overview
The Dexotromethorphan hydrobromide and Chlorpheniramine Maleate is a combination of two drugs used to help relieve common cold and cough symptoms and allergies.
Chlorpheniramine Maleate
The Chlorpheniramine Maleate works by reducing the ill effects of histamine, a substance that causes allergic reactions.
Dextromethorphan Hydrobromide
Dextromethorphan hydrobromide, on the other hand, works by blocking the transmission of nerve signals from the cough center in the brain all the way to the muscles that actually produce it.
Dextromethorphan hydrobromide and chlorpheniramine Maleate‘s Composition
The syrup mainly has two active ingredients, and its composition is:
Dextromethorphan Hydrobromide
This is a non-narcotic cough suppressant that works on reducing the effects of the cough center in the brain. This means that the urge you have to cough is actually a signal from the brain, and this medicine helps suppress that. It is particularly effective for treating dry cough. It is chemically related to the morphine compounds without the opioid effects, thus making it safe for over-the-counter use at recommended dosage. However, it has a half-life of 4 hour,s but in certain cases, this can extend up to 13 hours.
Chlorpheniramine Maleate
This is an antihistamine that blocks out the effects of histamine, a substance known to create allergic reactions. In fact, this drug helps bring relief to symptoms like sneezing, a runny nose, itchy eyes, and throat irritation. Chlorpheniramine Maleate has mild sedative properties that help individuals with respiratory issues to sleep.
Side Effects
In general cases, this combination syrup is considered harmless but some patients might complain of mild and common side effects such as:
- Drowsiness and Dizziness: The Chlorpheniramine Maleate’s sedative properties may be mild, but they are still somewhat active. It can cause sleepiness or lightheadedness thus, those activities that might cause concentration, like reading, driving, etc,. is not recommended after consumption of this syrup.
- Dry Mouth, Throat, and Nose: This is a common side effect of an antihistamine, which doesn’t require much attention. You can manage the effect by drinking water and chewing on some gum.
- Blurred Vision and Constipation: These might occur due to the anticholinergic effects of Chlorpheniramine’s composition and presence. Having a diet that’s rich in fiber and drinking more water can help manage it.
- Nausea, Vomiting, and Diarrhea: It may happen that some medicines cause a side effect that affects the gastrointestinal tract by causing discomfort.
Some of the more serious side effects might include:
- Severe Allergic Reactions: Symptoms like rash, itching, swelling or trouble breathing might happen in rare cases, but they would require immediate medical attention.
- Seizures or loss of consciousness: An overdose of this drug can lead to severe neurological effects, thus making it an immediate medical urgency.
Dosage Guidelines
The dosage of the Hydrobromide and Chlorpheniramine Maleate Syrup varies, depending on the age, medical condition, and weight of the patient. It is always recommended to follow the instructions that your doctor or healthcare provider gives. At the very least, you must read the medication labels and instructions. The general dosage guidelines include:
- Adults and Children above 12 years: For such patients, the typical dosage is 10 mL (2 teaspoons) every 4 to 6 hours, but it should not exceed 60 mL or 12 teaspoons in a matter of 24 hours. This could lead to an overdose.
- Children ages from 6 to 12 years: For such children, the dosage is typically restricted to 5 mL (1 teaspoon) every 4 to 6 hours, and it should not exceed 30 mL (6 teaspoons) in a matter of 24 hours.
- Children under 6 years: For such children, this medicine is not recommended unless it has been specifically directed or prescribed by a doctor.
- For Senior Citizens: This medicine is usually safe, but it should be recommended by a doctor or healthcare professional.
Missed Dose
In case you end up missing your dose, then you should take it as soon as you remember, unless it is too close to the next scheduled dose. However, do not double the missed dose to make up for it, as this might lead to an overdose.
Precautions
It is important to know about the precautions of the medicine before you consume it:
- Contraindications: In case you have allergies, or severe hypertension, coronary artery disease, urinary retention issues, or asthma, you should not have this unless your doctor recommends it.
- Pregnancy and Breastfeeding: For mothers who are pregnant or breastfeeding, this medicine may not be suitable, so it is advised to talk to your doctor before you take this medicine.
- Driving and Heavy Machinery: In case you are driving or working in heavy machinery, it is not recommended to have this medicine as it causes drowsiness and dizziness.
- Storage: The ideal way to store this syrup is at room temperature, around 20-25 degrees Celsius. Keep it away from light, moisture, or direct sunlight. Also, keep away from children and pets, and shake it before consuming.
Price
The price of the Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Syrup varies and depends on the brand, formulation and the area.
However, the prices of the medicine include:
- Corex DX Syrup (100ml): The approximate price is INR 45 per bottle in India.
- StayHappi Syrup (100ml): The prices range from INR 50 to 100, depending on the discounts and the retailer.
The generic versions are affordable in comparison to the branded options like Alex Syryp or Corex DX. Online pharmacies like 1mg or Pharmeasy offer competitive pricing and discounts, with some even offering cashbacks as compared to offline retailers. However, it is always recommended to check for expiration dates and such to ensure product quality.
Benefits
This combination drug is known to offer multiple benefits for individuals who are suffering from cold and allergic reactions. These benefits include:
- Relief from Cough: The Dextromethorphan Hydrobromide is known to effectively suppress dry, tickly cough by reducing the activity of the cough center in your brain. This is quite helpful for those individuals who have persistent coughing issues in daily life.
- Allergy Symptoms: The Chlorpheniramine Maleate targets histamine-causing symptoms like allergic reactions in the form of sneezing, runny nose, watery eyes, and more.
- Mild Sedative for Sleeping: The combination drug is also known to be a mild sedative, as the Chlorpheniramine Maleate has the property of sedation that may help those struggling with sleep due to their symptoms.
- Versatility: This combination syrup is quite effective for symptoms that are associated with viral infections, like the common cold, and allergic conditions, like hay fever, thus making it a go-to medicine for respiratory issues.
Conclusion
This Syrup is effective and is widely accessible as a syrup used to manage dry coughs and common allergy symptoms. it works double time as a dual agent – suppressing cough and also alleviating allergic symptoms – makes it quite an inevitable medicine composition for healthcare providers and professionals.
Refresh Date: August 22, 2025